{"id":1923,"date":"2025-11-24T09:02:03","date_gmt":"2025-11-24T09:02:03","guid":{"rendered":"https:\/\/bloodsense.ai\/medical-dictionary\/prn-meaning-as-needed-medication-guide\/"},"modified":"2026-07-16T15:18:46","modified_gmt":"2026-07-16T15:18:46","slug":"prn-%e5%90%ab%e4%b9%89%e6%8c%89%e9%9c%80%e7%94%a8%e8%8d%af%e6%8c%87%e5%8d%97","status":"publish","type":"post","link":"https:\/\/bloodsense.ai\/zh_cn\/%e5%8c%bb%e5%ad%a6%e8%af%8d%e5%85%b8\/prn-%e5%90%ab%e4%b9%89%e6%8c%89%e9%9c%80%e7%94%a8%e8%8d%af%e6%8c%87%e5%8d%97\/","title":{"rendered":"PRN \u542b\u4e49\uff1a\u6309\u9700\u7528\u836f\u53ca\u5176\u6ce8\u610f\u4e8b\u9879"},"content":{"rendered":"

\u5904\u65b9\u6807\u7b7e\u4e0a\u7684PRN\uff0c\u6e90\u81ea\u4e24\u4e2a\u62c9\u4e01\u8bcd\uff1apro re nata\uff0c\u901a\u5e38\u8bd1\u4e3a\"\u89c6\u60c5\u51b5\u800c\u5b9a\"\uff0c\u6216\u66f4\u7b80\u5355\u5730\u8bf4\uff0c\"\u6309\u9700\u4f7f\u7528\"\u3002PRN\u8868\u793a\u8be5\u836f\u7269\u662f\u6709\u6761\u4ef6\u670d\u7528\u7684\u2014\u2014\u5f53\u67d0\u79cd\u7279\u5b9a\u75c7\u72b6\u51fa\u73b0\u65f6\u624d\u670d\u7528\uff0c\u800c\u4e0d\u662f\u6309\u65f6\u95f4\u8868\u670d\u7528\u3002<\/p>\n\n

\u6b63\u662f\u8fd9\u4e00\u6838\u5fc3\u6982\u5ff5\uff0c\u4f7fPRN\u6709\u522b\u4e8e\u60a8\u53ef\u80fd\u9047\u5230\u7684\u6240\u6709\u5176\u4ed6\u5242\u91cf\u7f29\u5199\u3002\u5b83\u4e5f\u662f\u5173\u4e8ePRN\u6700\u5e38\u89c1\u8bef\u89e3\u7684\u6839\u6e90\u3002PRN\u5e76\u4e0d\u610f\u5473\u7740\"\u968f\u65f6\u60f3\u7528\u5c31\u7528\"\u3002\u4e00\u4efd\u89c4\u8303\u7684PRN\u533b\u5631\u5305\u542b\u4e09\u4e2a\u72ec\u7acb\u7684\u9650\u5236\u6761\u4ef6\uff0c\u800c\u4eba\u4eec\u6700\u5bb9\u6613\u5ffd\u7565\u7684\uff0c\u662f24\u5c0f\u65f6\u5185\u5141\u8bb8\u4f7f\u7528\u7684\u6700\u5927\u5242\u91cf\u4e0a\u9650\u3002<\/p>\n\n

\u5728\u672c\u6307\u5357\u4e2d\uff0c\u60a8\u5c06\u4e86\u89e3 pro re nata \u7684\u771f\u6b63\u542b\u4e49\u3001\u5982\u4f55\u89e3\u8bfb PRN \u533b\u5631\u7684\u4e09\u4e2a\u7ec4\u6210\u90e8\u5206\u3001\u6309\u9700\u7528\u836f\u4e0e\u5b9a\u65f6\u7528\u836f\u6709\u4f55\u4e0d\u540c\u3001\u4e3a\u4f55\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u9700\u8981\u7279\u522b\u6ce8\u610f\uff0c\u4ee5\u53ca\u4e34\u5e8a\u533b\u751f\u5728 PRN \u4f7f\u7528\u4e0a\u81f3\u4eca\u4ecd\u5b58\u5728\u54ea\u4e9b\u5206\u6b67\u3002<\/p>\n\n

Pro re nata \u7684\u771f\u6b63\u542b\u4e49<\/h2>\n\n

Pro re nata \u662f\u62c9\u4e01\u8bed\uff0c\u62c6\u5f00\u6765\u770b\uff0c\u5927\u81f4\u610f\u601d\u662f\"\u4e3a\u6240\u53d1\u751f\u4e4b\u4e8b\"\u6216\"\u89c6\u60c5\u51b5\u800c\u5b9a\"\u3002\u533b\u5b66\u754c\u6cbf\u7528\u8fd9\u4e00\u77ed\u8bed\uff0c\u662f\u56e0\u4e3a\u5b83\u8868\u8fbe\u4e86\u4efb\u4f55\u5355\u4e00\u82f1\u8bed\u8bcd\u6c47\u90fd\u65e0\u6cd5\u51c6\u786e\u4f20\u8fbe\u7684\u542b\u4e49\uff1a\u7ed9\u836f\u662f\u7531\u67d0\u4e00\u4e8b\u4ef6\u89e6\u53d1\u7684\uff0c\u800c\u975e\u6309\u56fa\u5b9a\u65f6\u95f4\u8868\u6267\u884c\u3002<\/p>\n\n

\u5927\u591a\u6570\u7528\u836f\u9891\u6b21\u7f29\u5199\u56de\u7b54\u7684\u662f\"\u591a\u4e45\u670d\u4e00\u6b21\"\u8fd9\u4e2a\u95ee\u9898\u3002\u6bcf\u65e5\u4e00\u6b21\u7684\u533b\u5631\u4f7f\u7528 QD\u6bcf\u65e5\u4e00\u6b21\u7528\u836f\u7f29\u5199<\/a>\uff0c\u800c\u6bcf\u65e5\u4e24\u6b21\u7684\u533b\u5631\u5219\u6807\u6ce8 BID \u6bcf\u65e5\u4e24\u6b21\u7528\u836f\u8bf4\u660e<\/a>\u3002\u5728\u7f8e\u56fd\u5904\u65b9\u5b9e\u8df5\u4e2d\uff0c\u6bcf\u65e5\u56db\u6b21\u7684\u533b\u5631\u4f7f\u7528 QID \u6bcf\u65e5\u56db\u6b21\u7528\u836f\u8bf4\u660e<\/a>\uff0c\u800c\u82f1\u56fd\u5904\u65b9\u5219\u901a\u5e38\u4f7f\u7528 QDS \u6bcf\u65e5\u56db\u6b21\u7ed9\u836f\u6807\u6ce8<\/a> \u4ee3\u66ff\u3002\u4e00\u4e9b\u56fe\u8868\u4f1a\u5b8c\u6574\u5199\u51fa QDAY \u6bcf\u65e5\u4e00\u6b21\u5904\u65b9\u7f29\u5199<\/a> \u4ee5\u907f\u514d\u624b\u5199\u6df7\u6dc6\u3002<\/p>\n\n

PRN \u56de\u7b54\u7684\u662f\u4e00\u4e2a\u5b8c\u5168\u4e0d\u540c\u7684\u95ee\u9898\uff1a\"\u5728\u4ec0\u4e48\u6761\u4ef6\u4e0b\uff1f\"\u5b83\u5c5e\u4e8e\u53e6\u4e00\u4e2a\u7c7b\u522b\u3002\u7761\u524d\u533b\u5631\u4f53\u73b0\u7684\u662f QHS \u7761\u524d\u7528\u836f\u7f29\u5199<\/a> \u800c\u9910\u540e\u533b\u5631\u5219\u663e\u793a PC \u9910\u540e\u7528\u836f\u8bf4\u660e<\/a>\u3002\u6240\u6709\u8fd9\u4e9b\u90fd\u5c06\u5242\u91cf\u4e0e\u60a8\u53ef\u4ee5\u9884\u5224\u7684\u65f6\u95f4\u6216\u4e8b\u4ef6\u6302\u94a9\u3002\u800cPRN\u5219\u5c06\u5242\u91cf\u4e0e\u60a8\u65e0\u6cd5\u9884\u5224\u7684\u75c7\u72b6\u6302\u94a9\u3002<\/p>\n\n

\u8fd9\u5c31\u662f\u4e3a\u4ec0\u4e48PRN\u5f88\u5c11\u5355\u72ec\u51fa\u73b0\u3002\u5b83\u901a\u5e38\u4e0e\u7ed9\u836f\u9014\u5f84\u548c\u95f4\u9694\u65f6\u95f4\u4e00\u8d77\u6807\u6ce8\uff0c\u5c31\u50cf\u9014\u5f84\u548c\u9891\u6b21\u5728 PO TID \u53e3\u670d\u6bcf\u65e5\u4e09\u6b21\u7528\u836f\u8bf4\u660e<\/a>\u3002\u4e00\u884c\u5199\u7740\"PO q6h PRN for pain\"\u7684\u5185\u5bb9\uff0c\u7528\u516d\u4e2a\u5b57\u7b26\u5305\u542b\u4e86\u4e09\u6761\u6307\u793a\uff1a\u53e3\u670d\u3001\u95f4\u9694\u4e0d\u5c11\u4e8e\u6bcf\u516d\u5c0f\u65f6\u3001\u4e14\u4ec5\u5728\u60a8\u611f\u5230\u75bc\u75db\u65f6\u670d\u7528\u3002<\/p>\n\n

\u4e00\u4efd\u5b8c\u6574PRN\u533b\u5631\u7684\u4e09\u4e2a\u7ec4\u6210\u90e8\u5206<\/h2>\n\n

\u4e00\u4efd\u4e66\u5199\u89c4\u8303\u7684PRN\u533b\u5631\u5e76\u4e0d\u542b\u7cca\uff0c\u5b83\u5bf9\u4e09\u4ef6\u4e8b\u6709\u660e\u786e\u89c4\u5b9a\uff0c\u901a\u5e38\u8fd8\u4f1a\u52a0\u4e0a\u7b2c\u56db\u4ef6\u4e8b\u3002\u5982\u679c\u60a8\u7684\u836f\u54c1\u6807\u7b7e\u7f3a\u5c11\u5176\u4e2d\u4efb\u4f55\u4e00\u9879\uff0c\u8fd9\u662f\u4e00\u4e2a\u503c\u5f97\u5411\u836f\u5242\u5e08\u54a8\u8be2\u7684\u5408\u7406\u95ee\u9898\uff0c\u800c\u4e0d\u5e94\u81ea\u884c\u731c\u6d4b\u3002<\/p>\n\n

\u9996\u5148\u662f\u9002\u5e94\u75c7\uff1a\u5373\u8be5\u836f\u7269\u7684\u7528\u9014\u3002\"\u6309\u9700\u7528\u4e8e\u75bc\u75db\"\u4e0e\"\u6309\u9700\u7528\u4e8e\u6076\u5fc3\"\u662f\u4e24\u79cd\u4e0d\u540c\u7684\u8bb8\u53ef\uff0c\u9488\u5bf9\u5176\u4e2d\u4e00\u79cd\u75c7\u72b6\u83b7\u6279\u7684\u836f\u7269\u5e76\u4e0d\u81ea\u52a8\u9002\u7528\u4e8e\u53e6\u4e00\u79cd\u3002\u5176\u6b21\u662f\u6700\u77ed\u95f4\u9694\u65f6\u95f4\uff1a\u4e24\u6b21\u7528\u836f\u4e4b\u95f4\u5141\u8bb8\u7684\u6700\u77ed\u95f4\u9694\u3002\u5199\u4f5c\"q4h PRN\"\u6216\"q6h PRN\"\uff0c\u8fd9\u662f\u4e00\u4e2a\u4e0b\u9650\uff0c\u800c\u975e\u76ee\u6807\u3002\u7b49\u5f85\u66f4\u957f\u65f6\u95f4\u6ca1\u6709\u95ee\u9898\uff0c\u4f46\u7b49\u5f85\u65f6\u95f4\u4e0d\u8db3\u5219\u4e0d\u53ef\u4ee5\u3002<\/p>\n\n

24\u5c0f\u65f6\u5185\u7684\u6700\u5927\u7528\u91cf\u6392\u5728\u7b2c\u4e09\u4f4d\uff0c\u4e5f\u662f\u9ed8\u9ed8\u627f\u62c5\u6700\u591a\u5b89\u5168\u4fdd\u969c\u5de5\u4f5c\u7684\u90e8\u5206\u3002\u4ec5\u9760\u95f4\u9694\u65f6\u95f4\u672c\u8eab\u5e76\u4e0d\u80fd\u4fdd\u62a4\u60a8\uff0c\u56e0\u4e3a\u95f4\u9694\u65f6\u95f4\u53ef\u4ee5\u53e0\u52a0\u7d2f\u79ef\u300224\u5c0f\u65f6\u4e0a\u9650\u624d\u662f\u6700\u540e\u7684\u5b89\u5168\u9632\u7ebf\u3002<\/p>\n\n

PRN\u533b\u5631\u7684\u7ec4\u6210\u90e8\u5206<\/th>\u63a7\u5236\u5185\u5bb9<\/th>\u901a\u5e38\u5728\u6807\u7b7e\u4e0a\u7684\u663e\u793a\u65b9\u5f0f\",\"t9\"\uff1a\"\u6309\u9700\u7528\u4e8e\u75bc\u75db\"\u6216\"\u6309\u9700\u7528\u4e8e\u6076\u5fc3\"\",\"t10\"\uff1a\"\u6bcf6\u5c0f\u65f6\u4e00\u6b21\"\u6216\u7b80\u5199\"q6h\"\",\"t11\"\uff1a\"24\u5c0f\u65f6\u5185\u6700\u591a\u670d\u75284\u7247\"\",\"t12\"\uff1a\"\u82e5\u75c7\u72b6\u672a\u5f97\u5230\u63a7\u5236\uff0c\u8bf7\u8054\u7cfb\u60a8\u7684\u5904\u65b9\u533b\u751f\"<\/th><\/tr><\/thead>
\u9002\u5e94\u75c7<\/td>\u5141\u8bb8\u7528\u836f\u7684\u75c7\u72b6\u524d\u63d0<\/td>“\u6309\u9700\u6b62\u75db”\u6216“\u6309\u9700\u6b62\u5410”<\/td><\/tr>
\u6700\u77ed\u95f4\u9694\u65f6\u95f4<\/td>\u4e24\u6b21\u7528\u836f\u4e4b\u95f4\u5141\u8bb8\u7684\u6700\u77ed\u95f4\u9694<\/td>“\u6bcf6\u5c0f\u65f6\u4e00\u6b21”\u6216\u7b80\u5199“q6h”<\/td><\/tr>
24\u5c0f\u65f6\u5185\u6700\u5927\u7528\u91cf<\/td>\u4e0d\u8bba\u7528\u836f\u95f4\u9694\u5982\u4f55\uff0c\u603b\u91cf\u4e0a\u9650\u4e0d\u53d8<\/td>“24\u5c0f\u65f6\u5185\u6700\u591a\u670d\u75284\u7247”<\/td><\/tr>
\u5982\u679c\u836f\u7269\u65e0\u6548\u8be5\u600e\u4e48\u529e<\/td>\u5907\u9009\u65b9\u6848\uff0c\u56e0\u6b64\u4e0a\u9650\u5e76\u975e\u552f\u4e00\u7684\u7b54\u6848<\/td>“\u5982\u75c7\u72b6\u672a\u5f97\u5230\u63a7\u5236\uff0c\u8bf7\u8054\u7cfb\u60a8\u7684\u5904\u65b9\u533b\u751f”<\/td><\/tr><\/tbody><\/table><\/figure>\n\n

\u7efc\u5408\u4ee5\u4e0a\u5404\u90e8\u5206\uff0c\u4e00\u4e2a\u793a\u4f8b\u7528\u836f\u8bf4\u660e\u53ef\u80fd\u5982\u4e0b\uff1a\"\u6bcf6\u5c0f\u65f6\u6309\u9700\u53e3\u670d1\u7247\uff0c\u7528\u4e8e\u75bc\u75db\u300224\u5c0f\u65f6\u5185\u6700\u591a\u670d\u75284\u7247\u3002\"\u6b64\u793a\u4f8b\u4ec5\u7528\u4e8e\u8bf4\u660e\u5404\u90e8\u5206\u5982\u4f55\u76f8\u4e92\u914d\u5408\uff0c\u5e76\u975e\u9488\u5bf9\u4efb\u4f55\u8bfb\u8005\u7684\u7528\u836f\u5242\u91cf\u3002\u53ea\u6709\u60a8\u81ea\u5df1\u836f\u74f6\u4e0a\u7684\u6807\u7b7e\u624d\u63cf\u8ff0\u4e86\u60a8\u7684\u5177\u4f53\u7528\u836f\u60c5\u51b5\uff0c\u836f\u5242\u5e08\u53ef\u4ee5\u514d\u8d39\u9010\u884c\u4e3a\u60a8\u8be6\u7ec6\u8bb2\u89e3\u3002<\/p>\n\n

\u5b9a\u65f6\u7528\u836f\u3001\u6309\u9700\u7528\u836f\uff0c\u6216\u4e24\u8005\u517c\u6709<\/h2>\n\n

\u7406\u89e3\u6309\u9700\u7528\u836f\u6700\u6e05\u6670\u7684\u65b9\u5f0f\uff0c\u662f\u5c06\u5176\u4e0e\u5b9a\u65f6\u533b\u5631\uff08\u6709\u65f6\u79f0\u4e3a\u5e38\u89c4\u533b\u5631\uff09\u8fdb\u884c\u5bf9\u6bd4\u3002\u5b9a\u65f6\u7528\u836f\u7531\u65f6\u949f\u9a71\u52a8\uff0c\u800c\u6309\u9700\u7528\u836f\u5219\u7531\u60a8\u81ea\u8eab\u7684\u9700\u6c42\u9a71\u52a8\u3002<\/p>\n\n

\u95ee\u9898<\/th>\u5b9a\u65f6\u533b\u5631<\/th>\u6309\u9700\u533b\u5631<\/th><\/tr><\/thead>
\u4ec0\u4e48\u89e6\u53d1\u4e00\u6b21\u7528\u836f\uff1f<\/td>\u65f6\u949f\u5230\u8fbe\u8bbe\u5b9a\u65f6\u95f4<\/td>\u51fa\u73b0\u660e\u786e\u7684\u75c7\u72b6<\/td><\/tr>
\u8df3\u8fc7\u670d\u836f\u6709\u95ee\u9898\u5417\uff1f<\/td>\u901a\u5e38\u662f\u7684\uff0c\u56e0\u4e3a\u8fd9\u4f1a\u6253\u4e71\u6cbb\u7597\u8ba1\u5212<\/td>\u4e0d\u670d\u836f\u662f\u6b63\u5e38\u7ed3\u679c<\/td><\/tr>
\u4ec0\u4e48\u51b3\u5b9a\u7528\u836f\u4e0a\u9650\uff1f<\/td>\u5904\u65b9\u89c4\u5b9a\u7684\u7528\u836f\u9891\u7387\u672c\u8eab<\/td>\u6700\u77ed\u95f4\u9694\u65f6\u95f4\u52a0\u4e0a24\u5c0f\u65f6\u4e0a\u9650<\/td><\/tr>
\u5b83\u64c5\u957f\u4ec0\u4e48\uff1f<\/td>\u5728\u4f53\u5185\u7ef4\u6301\u7a33\u5b9a\u7684\u836f\u7269\u6d53\u5ea6<\/td>\u5e94\u5bf9\u65f6\u6709\u65f6\u65e0\u7684\u75c7\u72b6<\/td><\/tr><\/tbody><\/table><\/figure>\n\n

\u4e24\u8005\u5e76\u65e0\u4f18\u52a3\u4e4b\u5206\uff0c\u5b83\u4eec\u5404\u6709\u4e0d\u540c\u7684\u7528\u9014\uff0c\u8fd9\u4e5f\u662f\u4e3a\u4ec0\u4e48\u8bb8\u591a\u6cbb\u7597\u65b9\u6848\u4f1a\u540c\u65f6\u4f7f\u7528\u4e24\u8005\u3002\u4e00\u4f4d\u672f\u540e\u6062\u590d\u7684\u60a3\u8005\uff0c\u53ef\u80fd\u5168\u5929\u6301\u7eed\u4f7f\u7528\u4e00\u79cd\u5b9a\u65f6\u670d\u7528\u7684\u57fa\u7840\u836f\u7269\uff0c\u5c06\u75bc\u75db\u7ef4\u6301\u5728\u53ef\u63a7\u7684\u6700\u4f4e\u6c34\u5e73\uff0c\u540c\u65f6\u914d\u5408\u4e00\u79cdPRN\u836f\u7269\uff0c\u7528\u4e8e\u5e94\u5bf9\u4ecd\u4f1a\u7a81\u53d1\u7684\u75bc\u75db\u52a0\u5267\u3002\u4e34\u5e8a\u533b\u751f\u5c06\u8fd9\u7c7b\u7a81\u53d1\u60c5\u51b5\u79f0\u4e3a\"\u7a81\u7834\u6027\u75c7\u72b6\"\uff0c\u800cPRN\u5242\u91cf\u7684\u5b58\u5728\u6b63\u662f\u4e3a\u4e86\u5e94\u5bf9\u8fd9\u79cd\u60c5\u51b5\u3002<\/p>\n\n

\u4e86\u89e3\u4e00\u79cd\u836f\u7269\u5c5e\u4e8e\u54ea\u4e2a\u7c7b\u522b\uff0c\u4f1a\u6539\u53d8\u60a8\u5bf9\u5f85\u5b83\u7684\u65b9\u5f0f\u3002\u56e0\u4e3a\u611f\u89c9\u826f\u597d\u5c31\u505c\u7528\u5b9a\u65f6\u836f\u7269\uff0c\u53ef\u80fd\u4f1a\u4f7f\u6cbb\u7597\u524d\u529f\u5c3d\u5f03\u3002\u67d0\u5929\u4e0d\u9700\u8981\u4f7f\u7528\u6309\u9700\u836f\u7269\uff0c\u610f\u5473\u7740\u5b83\u6b63\u5728\u6309\u9884\u671f\u53d1\u6325\u4f5c\u7528\u3002\u5c06\u4e24\u8005\u6df7\u6dc6\u4f1a\u5728\u4e24\u4e2a\u65b9\u5411\u4e0a\u9020\u6210\u95ee\u9898\uff0c\u800c\u4e24\u4e2a\u65b9\u5411\u90fd\u4f1a\u5e26\u6765\u4f24\u5bb3\u3002<\/p>\n\n

24\u5c0f\u65f6\u4e0a\u9650\uff0c\u4ee5\u53ca\u4e3a\u4f55\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u5bb9\u6613\u88ab\u5ffd\u89c6<\/h2>\n\n

24\u5c0f\u65f6\u6700\u5927\u7528\u91cf\u542c\u8d77\u6765\u50cf\u662f\u7e41\u7410\u7684\u6ce8\u610f\u4e8b\u9879\uff0c\u76f4\u5230\u60a8\u4e86\u89e3\u5b83\u5728\u65e0\u4eba\u5bdf\u89c9\u7684\u60c5\u51b5\u4e0b\u6709\u591a\u5bb9\u6613\u88ab\u8d85\u51fa\u3002\u6700\u5178\u578b\u7684\u4f8b\u5b50\u5c31\u662f\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\uff0c\u5728\u7f8e\u56fd\u4ee5\u5916\u901a\u5e38\u79f0\u4e3a\u6251\u70ed\u606f\u75db\uff08paracetamol\uff09\u3002<\/p>\n\n

\u6839\u636e\u7f8e\u56fd\u98df\u54c1\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\u7684\u8d44\u6599\uff0c\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u5b58\u5728\u4e8e\u6570\u767e\u79cd\u975e\u5904\u65b9\u836f\u548c\u5904\u65b9\u836f\u4ea7\u54c1\u4e2d\u3002\u5b83\u53ef\u80fd\u662f\u552f\u4e00\u7684\u6d3b\u6027\u6210\u5206\uff0c\u4e5f\u53ef\u80fd\u4e0e\u5176\u4ed6\u6210\u5206\u6df7\u5408\u4f7f\u7528\u3002\u5728\u5904\u65b9\u6807\u7b7e\u4e0a\uff0c\u5b83\u8fd8\u4ee5\u591a\u79cd\u7f29\u5199\u5f62\u5f0f\u51fa\u73b0\uff0c\u5305\u62ecAPAP\u3001Acetaminoph\u3001Acetaminop\u3001Acetamin\u548cAcetam\u3002\u56e0\u6b64\uff0c\u4e00\u4e2a\u4eba\u53ef\u80fd\u540c\u65f6\u670d\u7528\u4e00\u79cdPRN\u6b62\u75db\u836f\u3001\u4e00\u79cdPRN\u611f\u5192\u6d41\u611f\u836f\u548c\u4e00\u79cd\u591c\u95f4\u7528\u836f\uff0c\u5374\u4ece\u4e09\u79cd\u836f\u7269\u4e2d\u90fd\u6444\u5165\u4e86\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\uff0c\u800c\u672a\u80fd\u4ece\u4efb\u4f55\u4e00\u79cd\u4e2d\u8bc6\u522b\u51fa\u6765\u3002<\/p>\n\n

FDA\u7684\u7acb\u573a\u660e\u786e\uff1a\u4e0d\u8981\u540c\u65f6\u4f7f\u7528\u591a\u79cd\u542b\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u7684\u4ea7\u54c1\uff0c\u5373\u4f7f\u75bc\u75db\u6216\u53d1\u70e7\u6301\u7eed\uff0c\u4e5f\u4e0d\u8981\u8d85\u8fc7\u6807\u7b7e\u4e0a\u6ce8\u660e\u7684\u5242\u91cf\uff0c\u5e76\u4e14\u8981\u4e86\u89e3\u670d\u7528\u8fc7\u91cf\u53ef\u80fd\u5bfc\u81f4\u809d\u8870\u7aed\u751a\u81f3\u6b7b\u4ea1\u3002\u8be5\u673a\u6784\u516c\u5e03\u4e86\u6210\u4eba\u572824\u5c0f\u65f6\u5185\u7684\u6700\u5927\u603b\u5242\u91cf\uff0c\u8be5\u6570\u5b57\u5370\u5728\u4ea7\u54c1\u6807\u7b7e\u4e0a\uff0c\u60a8\u5e94\u76f4\u63a5\u67e5\u9605\u6807\u7b7e\uff0c\u800c\u975e\u4f9d\u8d56\u6587\u7ae0\u4e2d\u7684\u8bf4\u660e\u3002FDA\u8fd8\u4ece\u4ea7\u54c1\u5c42\u9762\u91c7\u53d6\u4e86\u63aa\u65bd\uff0c\u9650\u5236\u5904\u65b9\u590d\u65b9\u4ea7\u54c1\u4e2d\u6bcf\u4e2a\u5242\u91cf\u5355\u4f4d\u6240\u542b\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u7684\u91cf\uff0c\u5e76\u5efa\u8bae\u5982\u679c\u60a8\u60a3\u6709\u809d\u75c5\uff0c\u5728\u4f7f\u7528\u524d\u5e94\u54a8\u8be2\u533b\u7597\u4e13\u4e1a\u4eba\u5458\u3002<\/p>\n\n

\u7f8e\u56fd\u56fd\u5bb6\u7cd6\u5c3f\u75c5\u3001\u6d88\u5316\u548c\u80be\u810f\u75be\u75c5\u7814\u7a76\u6240\u5728\u5176LiverTox\u8d44\u6e90\u4e2d\u6e05\u695a\u5730\u9610\u660e\u4e86\u751f\u7269\u5b66\u539f\u56e0\uff1a\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u5728\u4f4e\u5242\u91cf\u4e0b\u65e0\u5bb3\uff0c\u4f46\u8fc7\u91cf\u65f6\u5bf9\u809d\u810f\u6709\u76f4\u63a5\u635f\u4f24\u4f5c\u7528\uff0c\u5373\u4f7f\u5728\u6cbb\u7597\u5242\u91cf\u4e0b\u4e5f\u53ef\u80fd\u5bfc\u81f4\u809d\u9176\u6682\u65f6\u5347\u9ad8\u3002\u6b63\u56e0\u5982\u6b64\uff0c\u5f53\u5bf9\u4e59\u9170\u6c28\u57fa\u915a\u4f7f\u7528\u91cf\u8f83\u5927\u6216\u65f6\u95f4\u8f83\u957f\u65f6\uff0c\u4e34\u5e8a\u533b\u751f\u901a\u5e38\u4f1a\u5f00\u5177 ALT\u809d\u9176\u68c0\u6d4b<\/a>\uff0c\u6839\u636e\u68c0\u67e5\u7ed3\u679c\uff0c\u4ed6\u4eec\u53ef\u80fd\u8fd8\u4f1a\u589e\u52a0\u4e00\u9879 ALP \u78b1\u6027\u78f7\u9178\u9176\u68c0\u6d4b<\/a> \u4ee5\u8fdb\u4e00\u6b65\u4e86\u89e3\u662f\u5426\u4e5f\u6d89\u53ca\u80c6\u6c41\u6d41\u52a8\u95ee\u9898\u3002<\/p>\n\n

\u7f8e\u56fd\u56fd\u5bb6\u533b\u5b66\u56fe\u4e66\u9986\u5c31\u53e6\u4e00\u7c7b\u5e38\u89c1\u7684\u6309\u9700\u6b62\u75db\u836f\u63d0\u51fa\u4e86\u7c7b\u4f3c\u89c2\u70b9\u3002\u975e\u753e\u4f53\u6297\u708e\u836f\uff08\u5982\u5e03\u6d1b\u82ac\u548c\u8418\u666e\u751f\uff09\u5728\u670d\u7528\u91cf\u8d85\u8fc7\u63a8\u8350\u5242\u91cf\u65f6\uff0c\u53ef\u80fd\u5f15\u8d77\u6076\u5fc3\u3001\u80c3\u75db\u6216\u80c3\u6e83\u75a1\u3002\u5bf9\u4e8e\u4efb\u4f55\u6309\u9700\u7528\u836f\uff0c\u5b9e\u9645\u53ef\u884c\u7684\u505a\u6cd5\u90fd\u662f\u4e00\u6837\u7684\uff1a\u4ed4\u7ec6\u9605\u8bfb\u5b8c\u6574\u7684\u6210\u5206\u5217\u8868\uff0c\u800c\u4e0d\u4ec5\u4ec5\u770b\u54c1\u724c\u540d\u79f0\uff0c\u5e76\u8bf7\u836f\u5242\u5e08\u68c0\u67e5\u836f\u7269\u7ec4\u5408\u662f\u5426\u5b89\u5168\u3002<\/p>\n\n

\u5173\u4e8e\u6309\u9700\u7528\u836f\uff08PRN\uff09\u771f\u6b63\u5b58\u5728\u4e89\u8bae\u7684\u9886\u57df<\/h2>\n\n

\u6309\u9700\u7528\u836f\u5e76\u975e\u4e00\u79cd\u6ca1\u6709\u4e89\u8bae\u7684\u6210\u719f\u5de5\u5177\u3002\u6709\u4e24\u4e2a\u9886\u57df\u5b58\u5728\u771f\u5b9e\u7684\u4e13\u4e1a\u5206\u6b67\uff0c\u6709\u5fc5\u8981\u5982\u5b9e\u8bf4\u660e\uff0c\u4f46\u65e0\u9700\u5c06\u5176\u6e32\u67d3\u6210\u4ee4\u4eba\u62c5\u5fe7\u7684\u95ee\u9898\u3002<\/p>\n\n

\u6309\u9700\u4f7f\u7528\u963f\u7247\u7c7b\u836f\u7269<\/h3>\n\n

\u963f\u7247\u7c7b\u836f\u7269\u5e38\u4ee5PRN\uff08\u6309\u9700\uff09\u65b9\u5f0f\u5f00\u5177\uff0c\u7528\u4e8e\u7f13\u89e3\u4e2d\u91cd\u5ea6\u75bc\u75db\uff0c\u5c24\u5176\u662f\u5916\u4f24\u6216\u624b\u672f\u540e\u3002\u7f8e\u56fd\u56fd\u5bb6\u533b\u5b66\u56fe\u4e66\u9986\u6307\u51fa\uff0c\u6b64\u7c7b\u836f\u7269\u7597\u6548\u663e\u8457\uff0c\u4f46\u53ef\u80fd\u5f15\u53d1\u4e25\u91cd\u526f\u4f5c\u7528\uff0c\u5e76\u5b58\u5728\u6210\u763e\u98ce\u9669\uff0c\u987b\u5728\u533b\u751f\u6307\u5bfc\u4e0b\u4f7f\u7528\u3002\u8fd9\u79cd\u77db\u76fe\u5728\u7ed3\u6784\u4e0a\u662f\u56fa\u6709\u7684\uff1a\u6309\u9700\u533b\u5631\u5c06\u7528\u836f\u65f6\u673a\u7684\u51b3\u5b9a\u6743\u4ea4\u7ed9\u60a3\u8005\uff0c\u8fd9\u6b63\u662f\u5b83\u7075\u6d3b\u54cd\u5e94\u7684\u4f18\u52bf\u6240\u5728\uff0c\u4e5f\u6b63\u662f\u5242\u91cf\u4e0a\u9650\u81f3\u5173\u91cd\u8981\u7684\u539f\u56e0\u3002\u8fd9\u5e76\u4e0d\u610f\u5473\u7740\u60a8\u5e94\u8be5\u62d2\u7edd\u533b\u751f\u5f00\u5177\u7684\u836f\u7269\uff0c\u800c\u662f\u63d0\u9192\u60a8\u4e86\u89e3\u81ea\u5df1\u7684\u7528\u836f\u9650\u5ea6\uff0c\u5e76\u5728\u836f\u6548\u4e0d\u8db3\u65f6\u5c3d\u65e9\u544a\u77e5\u533b\u751f\u3002<\/p>\n\n

\u6309\u9700\u4f7f\u7528\u9547\u9759\u5242\u548c\u6297\u7cbe\u795e\u75c5\u836f\u7269<\/h3>\n\n

\u66f4\u4e3a\u6fc0\u70c8\u7684\u4e89\u8bba\u6d89\u53ca\u533b\u9662\u548c\u517b\u8001\u9662\u4e2d\u6309\u9700\u4f7f\u7528\u7cbe\u795e\u7c7b\u836f\u7269\u7684\u95ee\u9898\uff0c\u6b64\u7c7b\u836f\u7269\u901a\u5e38\u7528\u4e8e\u5904\u7406\u6fc0\u8d8a\u6216\u75db\u82e6\u72b6\u6001\u3002\u8fd9\u91cc\u7684\u4e89\u8bae\u4e3b\u8981\u4e0d\u5728\u4e8e\u6210\u763e\u95ee\u9898\uff0c\u800c\u5728\u4e8e\u8bc1\u636e\u548c\u4e60\u60ef\uff1a\u8fd9\u4e9b\u5242\u91cf\u7684\u4f7f\u7528\u7a76\u7adf\u662f\u56e0\u4e3a\u786e\u5b9e\u6709\u6548\uff0c\u8fd8\u662f\u4ec5\u4ec5\u56e0\u4e3a\u836f\u7269\u968f\u624b\u53ef\u5f97\u3001\u60c5\u51b5\u53c8\u96be\u4ee5\u5904\u7406\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u67d0\u4e9b\u8f83\u65b0\u7684\u836f\u7269\u660e\u786e\u4e0d\u9002\u5408\u6309\u9700\u4f7f\u7528\u3002\u5e03\u96f7\u54cc\u5511\uff08Brexpiprazole\uff09\u5728\u7f8e\u56fd\u88ab\u6279\u51c6\u7528\u4e8e\u6cbb\u7597\u963f\u5c14\u8328\u6d77\u9ed8\u75c5\u76f8\u5173\u7684\u6fc0\u8d8a\u75c7\u72b6\uff0c\u662f\u4e00\u79cd\u7ef4\u6301\u6027\u7528\u836f\uff0c\u6b63\u59822024\u5e74\u300a\u7f8e\u56fd\u533b\u7597\u4e3b\u4efb\u534f\u4f1a\u6742\u5fd7\u300b\u4e0a\u7684\u4e00\u7bc7\u7efc\u8ff0\u6240\u8bb0\u5f55\u7684\uff0c\u5b83\u4e0d\u5e94\u4f5c\u4e3a\u7a81\u53d1\u6027\u6fc0\u8d8a\u7684\u6309\u9700\u6cbb\u7597\u836f\u7269\u4f7f\u7528\u3002<\/p>\n\n

\u5982\u4f55\u8ba9\u6309\u9700\u7528\u836f\u771f\u6b63\u53d1\u6325\u4f5c\u7528<\/h2>\n\n

\u7531\u4e8e\u6309\u9700\u7528\u836f\u6ca1\u6709\u56fa\u5b9a\u65f6\u95f4\u8868\uff0c\u60a8\u6240\u670d\u7528\u7684\u5242\u91cf\u4e0d\u4f1a\u88ab\u81ea\u52a8\u8bb0\u5f55\u3002\u5927\u591a\u6570\u53ef\u907f\u514d\u7684\u95ee\u9898\u6b63\u662f\u4ece\u8fd9\u4e00\u758f\u6f0f\u5f00\u59cb\u7684\uff0c\u800c\u5f25\u8865\u8fd9\u4e00\u758f\u6f0f\u5176\u5b9e\u5e76\u4e0d\u590d\u6742\u3002<\/p>\n\n