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\n
\u9636\u6bb5\u6216\u7279\u5f81<\/th>\u5916\u89c2\u6216\u611f\u53d7<\/th><\/tr><\/thead>
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\u5929\u82b1\u5982\u4f55\u8bca\u65ad<\/h2>\n

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\n
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\u5929\u82b1\u4e0e\u7334\u75d8\u7814\u7a76\u7684\u6700\u65b0\u79d1\u5b66\u8fdb\u5c55<\/h2>\n

\u7531\u4e8e\u5929\u82b1\u5df2\u4e0d\u518d\u53d1\u751f\uff0c\u6700\u6709\u4ef7\u503c\u7684\u8fd1\u671f\u79d1\u5b66\u7814\u7a76\u6765\u81ea\u4e0e\u5176\u4eb2\u7f18\u5173\u7cfb\u5bc6\u5207\u7684\u7334\u75d8\u2014\u2014\u76f8\u540c\u7684\u836f\u7269\u548c\u75ab\u82d7\u53ef\u5728\u7334\u75d8\u60a3\u8005\u4e2d\u8fdb\u884c\u7814\u7a76\u3002\u6839\u636ePubMed\u6536\u5f55\u7684\u7814\u7a76\uff0c2025\u5e74\u4e00\u9879\u5173\u4e8e\u7279\u8003\u97e6\u62c9\uff08tecovirimat\uff09\u4e34\u5e8a\u8bd5\u9a8c\u7684\u7efc\u8ff0\u5f97\u51fa\u7ed3\u8bba\uff1a\u4e24\u9879\u89c4\u6a21\u6700\u5927\u7684\u968f\u673a\u7814\u7a76STOMP\u548cPALM007\u5747\u672a\u663e\u793a\u8be5\u836f\u7269\u80fd\u7f29\u77ed\u7334\u75d8\u75c5\u7a0b\uff0c\u5c3d\u7ba1\u65e9\u671f\u75c5\u4f8b\u62a5\u544a\u66fe\u7ed9\u51fa\u4ee4\u4eba\u9f13\u821e\u7684\u7ed3\u679c\uff08Dobrek\uff0c2025\u5e74\uff09\u3002\u8fd9\u5bf9\u60a8\u610f\u5473\u7740\u4ec0\u4e48\uff1a\u7279\u8003\u97e6\u62c9\u4f5c\u4e3a\u5929\u82b1\u5e94\u6025\u50a8\u5907\u836f\u7269\uff0c\u4f46\u76ee\u524d\u6700\u4f73\u8bc1\u636e\u8868\u660e\u5b83\u5e76\u975e\u7ecf\u8fc7\u9a8c\u8bc1\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4e00\u65e6\u771f\u6b63\u53d1\u751f\u5929\u82b1\u75ab\u60c5\uff0c\u4ecd\u5c06\u5728\u5f88\u5927\u7a0b\u5ea6\u4e0a\u4f9d\u8d56\u652f\u6301\u6027\u6cbb\u7597\u3002<\/p>\n

2025\u5e74\u4e00\u9879\u5173\u4e8e\u7334\u75d8\u7684\u5927\u578b\u7efc\u8ff0\u53d1\u73b0\uff0c\u4e24\u5242MVA-BN\u75ab\u82d7\uff08\u5373\u540c\u6837\u4e3a\u5929\u82b1\u7814\u53d1\u7684JYNNEOS\u75ab\u82d7\uff09\u5177\u6709\u826f\u597d\u7684\u5b89\u5168\u6027\u8bb0\u5f55\uff0c\u5728\u9884\u9632\u7334\u75d8\u65b9\u9762\u663e\u793a\u51fa\u4ee4\u4eba\u671f\u5f85\u7684\u6548\u679c\uff0c\u5305\u62ec\u5bf9\u514d\u75ab\u7cfb\u7edf\u8f83\u5f31\u7684\u4eba\u7fa4\u4e5f\u540c\u6837\u9002\u7528\uff08Viguier\u7b49\uff0c2025\u5e74\uff09\u3002\u8fd9\u5bf9\u60a8\u610f\u5473\u7740\u4ec0\u4e48\uff1a\u8fd9\u6b3e\u4e13\u4e3a\u5929\u82b1\u7814\u53d1\u7684\u975e\u590d\u5236\u578b\u75ab\u82d7\uff0c\u662f\u5e94\u5bf9\u8fd9\u4e00\u75c5\u6bd2\u5bb6\u65cf\u6700\u4ee4\u4eba\u653e\u5fc3\u7684\u5de5\u5177\uff1b\u5bf9\u4e8e\u7b26\u5408\u63a5\u79cd\u6761\u4ef6\u7684\u4eba\u7fa4\uff0c\u8fd9\u662f\u964d\u4f4e\u4ecd\u5728\u6d41\u884c\u7684\u6b63\u75d8\u75c5\u6bd2\u611f\u67d3\u98ce\u9669\u7684\u5207\u5b9e\u53ef\u884c\u7684\u65b9\u5f0f\u3002<\/p>\n

\u7814\u7a76\u4eba\u5458\u4e5f\u5728\u5f00\u53d1\u4e0b\u4e00\u4ee3\u5bf9\u6297\u624b\u6bb5\u30022026\u5e74\u7684\u4e00\u9879\u5b9e\u9a8c\u5ba4\u7814\u7a76\u4ece\u63a5\u79cd\u8fc7\u725b\u75d8\u75ab\u82d7\u7684\u4eba\u4f53\u5185\u5206\u79bb\u51fa\u4eba\u7c7b\u6297\u4f53\uff0c\u7ed3\u679c\u663e\u793a\u8fd9\u4e9b\u6297\u4f53\u80fd\u591f\u963b\u6b62\u5305\u62ec\u7334\u75d8\u75c5\u6bd2\u5728\u5185\u7684\u6b63\u75d8\u75c5\u6bd2\u5728\u7ec6\u80de\u95f4\u4f20\u64ad\uff0c\u5e76\u4fdd\u62a4\u5c0f\u9f20\u514d\u53d7\u81f4\u6b7b\u6027\u653b\u51fb\uff08Zhang et al., 2026\uff09\u3002\u8fd9\u5bf9\u60a8\u610f\u5473\u7740\u4ec0\u4e48\uff1a\u8fd9\u9879\u7814\u7a76\u76ee\u524d\u4ecd\u5904\u4e8e\u65e9\u671f\u4e34\u5e8a\u524d\u9636\u6bb5\uff0c\u5e76\u975e\u60a8\u73b0\u5728\u5c31\u80fd\u83b7\u53d6\u7684\u6cbb\u7597\u65b9\u6cd5\uff0c\u4f46\u5b83\u4e3a\u9776\u5411\u6297\u4f53\u7597\u6cd5\u6307\u660e\u4e86\u65b9\u5411\u2014\u2014\u8fd9\u7c7b\u7597\u6cd5\u672a\u6765\u6709\u671b\u4f5c\u4e3a\u73b0\u6709\u75ab\u82d7\u548c\u6297\u75c5\u6bd2\u836f\u7269\u7684\u8865\u5145\u3002<\/p>\n\n

\u5173\u952e\u672f\u8bed\u8868<\/h2>\n
\n
\u672f\u8bed<\/th>\u5b9a\u4e49<\/th><\/tr><\/thead>
\u5929\u82b1\u75c5\u6bd2<\/td>\u5bfc\u81f4\u5929\u82b1\u7684\u6b63\u75d8\u75c5\u6bd2\uff1b\u76ee\u524d\u5df2\u4e0d\u5728\u81ea\u7136\u754c\u4e2d\u4f20\u64ad\u3002<\/td><\/tr>\n
\u6b63\u75d8\u75c5\u6bd2<\/td>\u4e00\u7c7b\u76f8\u5173\u75c5\u6bd2\u7684\u603b\u79f0\uff0c\u5305\u62ec\u5929\u82b1\u75c5\u6bd2\u3001\u725b\u75d8\u75c5\u6bd2\u3001\u75d8\u82d7\u75c5\u6bd2\u548c\u7334\u75d8\u75c5\u6bd2\u3002<\/td><\/tr>\n
\u6839\u9664<\/td>\u5728\u5168\u7403\u8303\u56f4\u5185\u6c38\u4e45\u6d88\u706d\u67d0\u79cd\u75be\u75c5\uff1b\u5929\u82b1\u4e8e1980\u5e74\u5b9e\u73b0\u6839\u9664\u3002<\/td><\/tr>\n
\u91cd\u578b\u5929\u82b1<\/td>\u5929\u82b1\u7684\u5e38\u89c1\u91cd\u75c7\u7c7b\u578b\uff0c\u611f\u67d3\u8005\u6b7b\u4ea1\u7387\u7ea6\u4e3a30%\u3002<\/td><\/tr>\n
\u8f7b\u578b\u5929\u82b1<\/td>\u5929\u82b1\u7684\u8f83\u8f7b\u7c7b\u578b\uff0c\u75c5\u6b7b\u7387\u7ea6\u4e3a1%\u3002<\/td><\/tr>\n
\u6f5c\u4f0f\u671f<\/td>\u4ece\u63a5\u89e6\u75c5\u6bd2\u5230\u51fa\u73b0\u9996\u53d1\u75c7\u72b6\u4e4b\u95f47\u81f319\u5929\u7684\u6f5c\u4f0f\u671f\u3002<\/td><\/tr>\n
\u8113\u75b1<\/td>\u5929\u82b1\u76ae\u75b9\u7684\u5178\u578b\u8868\u73b0\uff0c\u4e3a\u9686\u8d77\u7684\u542b\u8113\u76ae\u635f\u3002<\/td><\/tr>\n
\u7279\u8003\u97e6\u745e\uff08TPOXX\uff09<\/td>\u4e00\u79cd\u7528\u4e8e\u5929\u82b1\u50a8\u5907\u7684\u6297\u75c5\u6bd2\u836f\u7269\uff0c\u4e5f\u7528\u4e8e\u6cbb\u7597\u7334\u75d8\u3002<\/td><\/tr>\n
MVA-BN\uff08JYNNEOS\uff09<\/td>\u4e00\u79cd\u975e\u590d\u5236\u578b\u75ab\u82d7\uff0c\u53ef\u540c\u65f6\u9884\u9632\u5929\u82b1\u548c\u7334\u75d8\u3002<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n

\u5e38\u89c1\u95ee\u9898<\/h2>\n

\u5929\u82b1\u73b0\u5728\u8fd8\u5b58\u5728\u5417\uff1f<\/h3>\n

\u4e0d\u5b58\u5728\u4e86\u3002\u5929\u82b1\u662f\u8fc4\u4eca\u4e3a\u6b62\u552f\u4e00\u88ab\u4eba\u7c7b\u5f7b\u5e95\u6839\u9664\u7684\u4f20\u67d3\u75c5\u3002\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u4e8e1980\u5e74\u5ba3\u5e03\u5929\u82b1\u7edd\u8ff9\uff0c\u81ea1977\u5e74\u4ee5\u6765\u518d\u672a\u51fa\u73b0\u8fc7\u81ea\u7136\u611f\u67d3\u75c5\u4f8b\u3002\u5929\u82b1\u75c5\u6bd2\u76ee\u524d\u4ec5\u4fdd\u5b58\u4e8e\u4e24\u4e2a\u5b89\u5168\u5b9e\u9a8c\u5ba4\u4e2d\uff0c\u4e00\u4e2a\u4f4d\u4e8e\u7f8e\u56fd\uff0c\u4e00\u4e2a\u4f4d\u4e8e\u4fc4\u7f57\u65af\uff0c\u5728\u4e25\u683c\u7ba1\u63a7\u4e0b\u7528\u4e8e\u79d1\u5b66\u7814\u7a76\u3002\u5f53\u524d\u6700\u4e3b\u8981\u7684\u9690\u60a3\u662f\u8be5\u75c5\u6bd2\u88ab\u7528\u4f5c\u751f\u7269\u6050\u6016\u6b66\u5668\u7684\u6781\u5c0f\u53ef\u80fd\u6027\uff0c\u8fd9\u4e5f\u662f\u5404\u56fd\u4ecd\u6301\u7eed\u50a8\u5907\u75ab\u82d7\u548c\u6297\u75c5\u6bd2\u836f\u7269\u7684\u539f\u56e0\u3002<\/p>\n

\u5929\u82b1\u7684\u4e3b\u8981\u75c7\u72b6\u6709\u54ea\u4e9b\uff1f<\/h3>\n

\u5929\u82b1\u7684\u6f5c\u4f0f\u671f\u7ea6\u4e3a7\u81f319\u5929\uff0c\u4e4b\u540e\u4f1a\u7a81\u7136\u51fa\u73b0\u9ad8\u70ed\u3001\u5267\u70c8\u5934\u75db\u3001\u80cc\u75db\u548c\u4e4f\u529b\u7b49\u75c7\u72b6\u30022\u81f34\u5929\u540e\u51fa\u73b0\u7279\u5f81\u6027\u76ae\u75b9\uff0c\u6700\u521d\u4ece\u9762\u90e8\u5f00\u59cb\uff0c\u968f\u540e\u8513\u5ef6\u81f3\u624b\u81c2\u548c\u817f\u90e8\u3002\u76ae\u75b9\u9010\u6e10\u6f14\u53d8\u4e3a\u575a\u786c\u7684\u6df1\u5c42\u6c34\u75b1\uff0c\u7ee7\u800c\u5f62\u6210\u5145\u6ee1\u8113\u6db2\u7684\u8113\u75b1\uff0c\u7ea6\u4e24\u5468\u540e\u7ed3\u75c2\uff0c\u901a\u5e38\u7559\u4e0b\u6c38\u4e45\u6027\u7622\u75d5\u3002\u4e0e\u6c34\u75d8\u4e0d\u540c\uff0c\u5929\u82b1\u7684\u6240\u6709\u76ae\u635f\u4f1a\u540c\u6b65\u7ecf\u5386\u5404\u4e2a\u53d1\u5c55\u9636\u6bb5\u3002<\/p>\n

\u5929\u82b1\u662f\u5982\u4f55\u88ab\u6839\u9664\u7684\uff1f<\/h3>\n

\u5929\u82b1\u901a\u8fc7\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u572820\u4e16\u7eaa60\u81f370\u5e74\u4ee3\u4e3b\u5bfc\u7684\u5168\u7403\u534f\u8c03\u75ab\u82d7\u63a5\u79cd\u8fd0\u52a8\u5f97\u4ee5\u6d88\u706d\u3002\u4e24\u4e2a\u5173\u952e\u56e0\u7d20\u4f7f\u8fd9\u4e00\u6210\u529f\u6210\u4e3a\u53ef\u80fd\uff1a\u8be5\u75c5\u6bd2\u53ea\u611f\u67d3\u4eba\u7c7b\uff0c\u6ca1\u6709\u52a8\u7269\u5bbf\u4e3b\u53ef\u4ee5\u85cf\u533f\uff0c\u4e14\u5df2\u6709\u6709\u6548\u75ab\u82d7\u3002\u536b\u751f\u5de5\u4f5c\u961f\u91c7\u7528\u4e86\u4e00\u79cd\"\u73af\u5f62\u63a5\u79cd\"\u7b56\u7565\uff0c\u5373\u627e\u5230\u6bcf\u4e00\u5904\u75ab\u60c5\uff0c\u5bf9\u5176\u5468\u56f4\u6240\u6709\u4eba\u8fdb\u884c\u63a5\u79cd\uff0c\u76f4\u5230\u5404\u5730\u7684\u4f20\u64ad\u94fe\u5168\u90e8\u5207\u65ad\u3002\u6700\u540e\u4e00\u4f8b\u81ea\u7136\u611f\u67d3\u75c5\u4f8b\u8bb0\u5f55\u4e8e1977\u5e74\u3002<\/p>\n

\u5929\u82b1\u6709\u6cbb\u7597\u65b9\u6cd5\u6216\u7279\u6548\u836f\u5417\uff1f<\/h3>\n

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