{"id":1876,"date":"2025-11-22T07:27:45","date_gmt":"2025-11-22T07:27:45","guid":{"rendered":"https:\/\/bloodsense.ai\/diseases\/sickle-cell-disease-guide-to-symptoms-and-treatments\/"},"modified":"2026-07-17T09:57:50","modified_gmt":"2026-07-17T09:57:50","slug":"sickle-cell-disease-guide-to-symptoms-and-treatments","status":"publish","type":"post","link":"https:\/\/bloodsense.ai\/ar\/diseases\/sickle-cell-disease-guide-to-symptoms-and-treatments\/","title":{"rendered":"\u0645\u0631\u0636 \u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0645\u0646\u062c\u0644\u064a: \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0648\u0627\u0644\u0623\u0633\u0628\u0627\u0628 \u0648\u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0648\u0627\u0644\u0639\u0644\u0627\u062c"},"content":{"rendered":"

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\u062a\u0628\u062f\u0623 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0639\u0627\u062f\u0629\u064b \u0641\u064a \u0627\u0644\u0633\u0646\u0629 \u0627\u0644\u0623\u0648\u0644\u0649 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631\u060c \u063a\u0627\u0644\u0628\u064b\u0627 \u0641\u064a \u0627\u0644\u0634\u0647\u0631 \u0627\u0644\u062e\u0627\u0645\u0633 \u0623\u0648 \u0627\u0644\u0633\u0627\u062f\u0633\u060c \u0648\u062a\u062a\u0641\u0627\u0648\u062a \u062a\u0641\u0627\u0648\u062a\u064b\u0627 \u0643\u0628\u064a\u0631\u064b\u0627 \u0645\u0646 \u0634\u062e\u0635 \u0644\u0622\u062e\u0631. \u064a\u064f\u0639\u0627\u0646\u064a \u0643\u062b\u064a\u0631\u0648\u0646 \u0645\u0646 \u0641\u0642\u0631 \u062f\u0645 \u0645\u0632\u0645\u0646 \u0648\u0625\u0631\u0647\u0627\u0642 \u062f\u0627\u0626\u0645 \u0646\u062a\u064a\u062c\u0629 \u0627\u0644\u062a\u062d\u0644\u0644 \u0627\u0644\u0645\u0633\u062a\u0645\u0631 \u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621\u060c \u0625\u0630 \u064a\u0639\u062c\u0632 \u0627\u0644\u062c\u0633\u0645 \u0639\u0646 \u062a\u0639\u0648\u064a\u0636 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0641\u0642\u0648\u062f\u0629 \u0628\u0627\u0644\u0633\u0631\u0639\u0629 \u0627\u0644\u0643\u0627\u0641\u064a\u0629 \u0641\u064a\u0642\u0644 \u0648\u0635\u0648\u0644 \u0627\u0644\u0623\u0643\u0633\u062c\u064a\u0646 \u0625\u0644\u0649 \u0627\u0644\u0623\u0646\u0633\u062c\u0629\u061b \u0648\u0644\u0645\u0639\u0631\u0641\u0629 \u0627\u0644\u0645\u0632\u064a\u062f \u0639\u0646 \u0647\u0630\u0627 \u0627\u0644\u0646\u0642\u0635 \u064a\u0645\u0643\u0646\u0643 \u0627\u0644\u0627\u0637\u0644\u0627\u0639 \u0639\u0644\u0649 \u0647\u0630\u0627 \u0627\u0644\u062f\u0644\u064a\u0644 \u062d\u0648\u0644 \u0623\u0639\u0631\u0627\u0636 \u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0648\u0623\u0633\u0628\u0627\u0628\u0647 \u0648\u0637\u0631\u0642 \u0639\u0644\u0627\u062c\u0647<\/a>. \u0648\u0627\u0644\u0633\u0645\u0629 \u0627\u0644\u0623\u0628\u0631\u0632 \u0644\u0647\u0630\u0627 \u0627\u0644\u0645\u0631\u0636 \u0647\u064a \u0646\u0648\u0628\u0629 \u0627\u0644\u0623\u0644\u0645\u060c \u0623\u0648 \u0645\u0627 \u064a\u064f\u0639\u0631\u0641 \u0628\u0627\u0644\u0623\u0632\u0645\u0629 \u0627\u0644\u0627\u0646\u0633\u062f\u0627\u062f\u064a\u0629 \u0627\u0644\u0648\u0639\u0627\u0626\u064a\u0629\u060c \u062d\u064a\u062b \u062a\u062a\u0633\u0628\u0628 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u0645\u0633\u062f\u0648\u062f\u0629 \u0641\u064a \u0623\u0644\u0645 \u0645\u0641\u0627\u062c\u0626 \u0642\u062f \u064a\u0636\u0631\u0628 \u0627\u0644\u0639\u0638\u0627\u0645 \u0623\u0648 \u0627\u0644\u0635\u062f\u0631 \u0623\u0648 \u0627\u0644\u0638\u0647\u0631 \u0623\u0648 \u0627\u0644\u0628\u0637\u0646\u060c \u0648\u064a\u0645\u062a\u062f \u0645\u0646 \u0633\u0627\u0639\u0627\u062a \u0625\u0644\u0649 \u0623\u064a\u0627\u0645.<\/p>\n

\u064a\u064f\u0635\u0627\u0628 \u0643\u062b\u064a\u0631\u0648\u0646 \u0623\u064a\u0636\u064b\u0627 \u0628\u0627\u0644\u064a\u0631\u0642\u0627\u0646\u060c \u0648\u0647\u0648 \u0627\u0635\u0641\u0631\u0627\u0631 \u0627\u0644\u062c\u0644\u062f \u0648\u0627\u0644\u0639\u064a\u0646\u064a\u0646\u060c \u0646\u062a\u064a\u062c\u0629 \u0625\u0641\u0631\u0627\u0632 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u062a\u062d\u0644\u0644\u0629 \u0644\u0635\u0628\u063a\u0629 \u062a\u064f\u0633\u0645\u0649 \u0627\u0644\u0628\u064a\u0644\u064a\u0631\u0648\u0628\u064a\u0646. \u0648\u0642\u062f \u064a\u064f\u0639\u0627\u0646\u064a \u0627\u0644\u0631\u0636\u0651\u0639 \u0645\u0646 \u062a\u0648\u0631\u0645 \u0645\u0624\u0644\u0645 \u0641\u064a \u0627\u0644\u064a\u062f\u064a\u0646 \u0648\u0627\u0644\u0642\u062f\u0645\u064a\u0646 \u064a\u064f\u0639\u0631\u0641 \u0628\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0623\u0635\u0627\u0628\u0639 (Dactylitis)\u060c \u0648\u0642\u062f \u064a\u0643\u0648\u0646 \u0623\u0648\u0644 \u0639\u0644\u0627\u0645\u0629 \u0645\u0644\u062d\u0648\u0638\u0629 \u0644\u0644\u0645\u0631\u0636. \u0648\u0644\u0623\u0646 \u0627\u0644\u0637\u062d\u0627\u0644 \u064a\u062a\u0636\u0631\u0631 \u0641\u064a \u0648\u0642\u062a \u0645\u0628\u0643\u0631\u060c \u064a\u0643\u0648\u0646 \u0627\u0644\u0623\u0637\u0641\u0627\u0644 \u0627\u0644\u0645\u0635\u0627\u0628\u0648\u0646 \u0628\u0645\u0631\u0636 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u062c\u0644\u064a\u0629 \u0623\u0643\u062b\u0631 \u0639\u0631\u0636\u0629 \u0644\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u062e\u0637\u064a\u0631\u0629.<\/p>\n\n

\n
\u0627\u0644\u0639\u0631\u0636 \u0627\u0644\u0634\u0627\u0626\u0639<\/th>\u0645\u0627 \u062a\u0634\u0645\u0644\u0647 \u0627\u0644\u0623\u0639\u0631\u0627\u0636 \u0639\u0627\u062f\u0629\u064b<\/th><\/tr><\/thead>
\u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0645\u0632\u0645\u0646 \u0648\u0627\u0644\u0625\u0631\u0647\u0627\u0642<\/td>\u062a\u0639\u0628 \u0645\u0633\u062a\u0645\u0631 \u0648\u0634\u062d\u0648\u0628 \u0648\u0636\u064a\u0642 \u0641\u064a \u0627\u0644\u062a\u0646\u0641\u0633 \u0628\u0633\u0628\u0628 \u0627\u0644\u0646\u0642\u0635 \u0627\u0644\u062f\u0627\u0626\u0645 \u0641\u064a \u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621<\/td><\/tr>\n
\u0646\u0648\u0628\u0627\u062a \u0627\u0644\u0623\u0644\u0645<\/td>\u0646\u0648\u0628\u0627\u062a \u0623\u0644\u0645 \u0645\u0641\u0627\u062c\u0626 \u0641\u064a \u0627\u0644\u0639\u0638\u0627\u0645 \u0623\u0648 \u0627\u0644\u0635\u062f\u0631 \u0623\u0648 \u0627\u0644\u0638\u0647\u0631 \u0623\u0648 \u0627\u0644\u0628\u0637\u0646 \u0639\u0646\u062f \u0627\u0646\u0633\u062f\u0627\u062f \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629<\/td><\/tr>\n
\u0627\u0644\u064a\u0631\u0642\u0627\u0646 (Jaundice)<\/td>\u0627\u0635\u0641\u0631\u0627\u0631 \u0627\u0644\u062c\u0644\u062f \u0648\u0628\u064a\u0627\u0636 \u0627\u0644\u0639\u064a\u0646\u064a\u0646 \u0646\u062a\u064a\u062c\u0629 \u062a\u0643\u0633\u0651\u0631 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621<\/td><\/tr>\n
\u062a\u0648\u0631\u0645 \u0627\u0644\u064a\u062f\u064a\u0646 \u0648\u0627\u0644\u0642\u062f\u0645\u064a\u0646<\/td>\u0627\u0646\u062a\u0641\u0627\u062e \u0645\u0624\u0644\u0645 \u064a\u064f\u0639\u0631\u0641 \u0628\u0627\u0644\u062a\u0647\u0627\u0628 \u0627\u0644\u0623\u0635\u0627\u0628\u0639 (Dactylitis)\u060c \u0648\u063a\u0627\u0644\u0628\u064b\u0627 \u0645\u0627 \u064a\u0643\u0648\u0646 \u0645\u0646 \u0623\u0648\u0644\u0649 \u0627\u0644\u0639\u0644\u0627\u0645\u0627\u062a \u0644\u062f\u0649 \u0627\u0644\u0631\u0636\u0651\u0639<\/td><\/tr>\n
\u0627\u0644\u0625\u0635\u0627\u0628\u0627\u062a \u0627\u0644\u0645\u062a\u0643\u0631\u0631\u0629<\/td>\u0627\u0631\u062a\u0641\u0627\u0639 \u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u062a\u0647\u0627\u0628\u0627\u062a \u062e\u0637\u064a\u0631\u0629 \u0628\u0633\u0628\u0628 \u062a\u0636\u0631\u0631 \u0627\u0644\u0637\u062d\u0627\u0644 \u0641\u064a \u0645\u0631\u062d\u0644\u0629 \u0645\u0628\u0643\u0631\u0629 \u0645\u0646 \u0627\u0644\u062d\u064a\u0627\u0629<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n

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\u0627\u0644\u0641\u062d\u0635 \u0627\u0644\u062a\u0623\u0643\u064a\u062f\u064a \u0647\u0648 \u0631\u062d\u0644\u0627\u0646 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 \u0627\u0644\u0643\u0647\u0631\u0628\u0627\u0626\u064a (Hemoglobin Electrophoresis)\u060c \u0627\u0644\u0630\u064a \u064a\u064f\u062c\u0631\u0649 \u0623\u062d\u064a\u0627\u0646\u0627\u064b \u0628\u062a\u0642\u0646\u064a\u0629 \u0627\u0644\u0643\u0631\u0648\u0645\u0627\u062a\u0648\u063a\u0631\u0627\u0641\u064a\u0627 \u0627\u0644\u0633\u0627\u0626\u0644\u0629 \u0639\u0627\u0644\u064a\u0629 \u0627\u0644\u0623\u062f\u0627\u0621 \u0623\u0648 \u0627\u0644\u062a\u0631\u0643\u064a\u0632 \u0627\u0644\u0643\u0647\u0631\u0628\u0627\u0626\u064a \u0645\u062a\u0633\u0627\u0648\u064a \u0627\u0644\u0634\u062d\u0646\u0629\u060c \u0648\u0647\u0648 \u064a\u0641\u0635\u0644 \u0628\u064a\u0646 \u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 \u0627\u0644\u0645\u062e\u062a\u0644\u0641\u0629 \u0648\u064a\u064f\u0638\u0647\u0631 \u0645\u0627 \u0625\u0630\u0627 \u0643\u0627\u0646 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 S \u0645\u0648\u062c\u0648\u062f\u0627\u064b \u0648\u0628\u0623\u064a \u0646\u0633\u0628\u0629. \u0648\u062a\u064f\u0643\u0645\u0644 \u0627\u0644\u0641\u062d\u0648\u0635\u0627\u062a \u0627\u0644\u062f\u0645\u0648\u064a\u0629 \u0627\u0644\u062f\u0627\u0639\u0645\u0629 \u0627\u0644\u0635\u0648\u0631\u0629 \u0627\u0644\u062a\u0634\u062e\u064a\u0635\u064a\u0629\u061b \u0625\u0630 \u064a\u0631\u0627\u062c\u0639 \u0627\u0644\u0623\u0637\u0628\u0627\u0621 \u0646\u062a\u0627\u0626\u062c \u0635\u0648\u0631\u0629 \u0627\u0644\u062f\u0645 \u0627\u0644\u0643\u0627\u0645\u0644\u0629 (CBC)<\/a> \u0644\u062a\u0642\u064a\u064a\u0645 \u062f\u0631\u062c\u0629 \u0641\u0642\u0631 \u0627\u0644\u062f\u0645\u060c \u0643\u0645\u0627 \u064a\u0641\u062d\u0635\u0648\u0646 \u0639\u062f\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 (Reticulocytes) \u0627\u0644\u0630\u064a \u064a\u064f\u0628\u064a\u0651\u0646 \u0645\u062f\u0649 \u0633\u0631\u0639\u0629 \u0646\u062e\u0627\u0639 \u0627\u0644\u0639\u0638\u0645 \u0641\u064a \u0625\u0646\u062a\u0627\u062c \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621 \u0627\u0644\u062c\u062f\u064a\u062f\u0629<\/a>. \u0648\u0644\u0623\u0646 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u062c\u0644\u064a\u0629 \u062a\u062a\u0641\u062a\u062a \u0645\u0628\u0643\u0631\u0627\u064b\u060c \u0643\u062b\u064a\u0631\u0627\u064b \u0645\u0627 \u062a\u0642\u064a\u0633 \u0627\u0644\u0645\u062e\u062a\u0628\u0631\u0627\u062a \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0628\u064a\u0644\u064a\u0631\u0648\u0628\u064a\u0646 \u0627\u0644\u0630\u064a \u064a\u0631\u062a\u0641\u0639 \u0639\u0646\u062f \u062a\u062d\u0644\u0644 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621<\/a> \u0648\u0627\u0646\u0638\u0631 \u0625\u0644\u0649 \u0625\u0646\u0632\u064a\u0645 \u0644\u0627\u0643\u062a\u0627\u062a \u062f\u064a\u0647\u064a\u062f\u0631\u0648\u062c\u064a\u0646\u0627\u0632 (LDH) \u0628\u0648\u0635\u0641\u0647 \u0645\u0624\u0634\u0631\u064b\u0627 \u0625\u0636\u0627\u0641\u064a\u064b\u0627 \u0639\u0644\u0649 \u062a\u0643\u0633\u0651\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627\u061b \u064a\u0645\u0643\u0646\u0643 \u0623\u0646 \u062a\u0641\u0647\u0645 \u0645\u0627 \u0627\u0644\u0630\u064a \u064a\u0643\u0634\u0641\u0647 \u062a\u062d\u0644\u064a\u0644 LDH \u0641\u064a \u0627\u0644\u062f\u0645 \u0639\u0646 \u0645\u0639\u062f\u0644 \u062a\u062c\u062f\u062f \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621<\/a>. \u0642\u062f \u064a\u064f\u0638\u0647\u0631 \u062a\u062d\u0644\u064a\u0644 \u0644\u0637\u0627\u062e\u0629 \u0627\u0644\u062f\u0645 \u062a\u062d\u062a \u0627\u0644\u0645\u062c\u0647\u0631 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0646\u062c\u0644\u064a\u0629 \u0628\u0634\u0643\u0644 \u0645\u0628\u0627\u0634\u0631\u060c \u0643\u0645\u0627 \u064a\u0645\u0643\u0646 \u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0645\u0627 \u0642\u0628\u0644 \u0627\u0644\u0648\u0644\u0627\u062f\u0629 \u0623\u0648 \u0627\u0644\u0643\u0634\u0641 \u0639\u0646 \u062d\u0627\u0645\u0644\u064a \u0627\u0644\u0645\u0631\u0636 \u062a\u0623\u0643\u064a\u062f \u0627\u0644\u062c\u0627\u0646\u0628 \u0627\u0644\u062c\u064a\u0646\u064a \u0642\u0628\u0644 \u0627\u0644\u062d\u0645\u0644 \u0623\u0648 \u062e\u0644\u0627\u0644\u0647.<\/p>\n\n

\n
\u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631<\/th>\u0645\u0627 \u0627\u0644\u0630\u064a \u064a\u0643\u0634\u0641\u0647<\/th>\u062f\u0648\u0631 \u0627\u0644\u0627\u062e\u062a\u0628\u0627\u0631\u0627\u062a \u0641\u064a \u0627\u0644\u062a\u0634\u062e\u064a\u0635<\/th><\/tr><\/thead>
\u0641\u062d\u0635 \u062d\u062f\u064a\u062b\u064a \u0627\u0644\u0648\u0644\u0627\u062f\u0629<\/td>\u0625\u0634\u0627\u0631\u0629 \u0645\u0628\u0643\u0631\u0629 \u0639\u0644\u0649 \u0648\u062c\u0648\u062f \u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 \u063a\u064a\u0631 \u0637\u0628\u064a\u0639\u064a \u0645\u0646 \u0639\u064a\u0646\u0629 \u0648\u062e\u0632 \u0627\u0644\u0643\u0639\u0628<\/td>\u0627\u0644\u062e\u0637\u0648\u0629 \u0627\u0644\u0623\u0648\u0644\u0649\u060c \u062a\u064f\u062c\u0631\u0649 \u0644\u0643\u0644 \u0645\u0648\u0644\u0648\u062f \u0641\u064a \u0627\u0644\u0648\u0644\u0627\u064a\u0627\u062a \u0627\u0644\u0645\u062a\u062d\u062f\u0629<\/td><\/tr>\n
\u0631\u062d\u0644\u0627\u0646 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 \u0627\u0644\u0643\u0647\u0631\u0628\u0627\u0626\u064a \u0623\u0648 HPLC<\/td>\u0627\u0644\u0623\u0646\u0648\u0627\u0639 \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0648\u0643\u0645\u064a\u0627\u062a \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646\u060c \u0628\u0645\u0627 \u0641\u064a\u0647\u0627 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 S<\/td>\u064a\u0624\u0643\u062f \u0627\u0644\u062a\u0634\u062e\u064a\u0635 \u0648\u0627\u0644\u0646\u0645\u0637 \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0645\u062d\u062f\u062f<\/td><\/tr>\n
\u0635\u0648\u0631\u0629 \u0627\u0644\u062f\u0645 \u0627\u0644\u0643\u0627\u0645\u0644\u0629 (CBC)<\/td>\u0639\u062f\u062f \u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621 \u0648\u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646<\/td>\u064a\u0642\u064a\u0633 \u0645\u062f\u0649 \u0634\u062f\u0629 \u0641\u0642\u0631 \u0627\u0644\u062f\u0645<\/td><\/tr>\n
\u0639\u062f\u062f \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0634\u0628\u0643\u064a\u0629 (\u0627\u0644\u0631\u064a\u062a\u064a\u0643\u064a\u0648\u0644\u0648\u0633\u064a\u062a)<\/td>\u0645\u062f\u0649 \u0633\u0631\u0639\u0629 \u0625\u0646\u062a\u0627\u062c \u0646\u062e\u0627\u0639 \u0627\u0644\u0639\u0638\u0645 \u0644\u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621 \u0627\u0644\u062c\u062f\u064a\u062f\u0629<\/td>\u064a\u064f\u0638\u0647\u0631 \u0627\u0633\u062a\u062c\u0627\u0628\u0629 \u0627\u0644\u0646\u062e\u0627\u0639 \u0644\u0644\u0641\u0642\u062f \u0627\u0644\u0645\u0633\u062a\u0645\u0631 \u0641\u064a \u0627\u0644\u062e\u0644\u0627\u064a\u0627<\/td><\/tr>\n
\u0627\u0644\u0628\u064a\u0644\u064a\u0631\u0648\u0628\u064a\u0646 \u0648\u0625\u0646\u0632\u064a\u0645 LDH<\/td>\u0645\u0648\u0627\u062f \u062a\u064f\u0637\u0644\u0642 \u0639\u0646\u062f \u062a\u0643\u0633\u0651\u0631 \u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621<\/td>\u062a\u0639\u0643\u0633 \u062f\u0631\u062c\u0629 \u062a\u0643\u0633\u0651\u0631 \u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621<\/td><\/tr>\n<\/tbody><\/table><\/figure>\n\n

\u0627\u0644\u0639\u0644\u0627\u062c \u0648\u0627\u0644\u0645\u062a\u0627\u0628\u0639\u0629<\/h2>\n

\u062a\u064f\u0635\u0645\u064e\u0651\u0645 \u062e\u0637\u0629 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0648\u0641\u0642 \u0627\u062d\u062a\u064a\u0627\u062c\u0627\u062a \u0643\u0644 \u0634\u062e\u0635\u060c \u0648\u062a\u0647\u062f\u0641 \u0625\u0644\u0649 \u062a\u0642\u0644\u064a\u0644 \u0627\u0644\u0623\u0632\u0645\u0627\u062a \u0648\u062a\u062e\u0641\u064a\u0641 \u0627\u0644\u0623\u0644\u0645 \u0648\u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0627\u0644\u0645\u0636\u0627\u0639\u0641\u0627\u062a. \u064a\u064f\u0639\u062f\u0651 \u0647\u064a\u062f\u0631\u0648\u0643\u0633\u064a\u0648\u0631\u064a\u0627 (Hydroxyurea) \u0627\u0644\u0631\u0643\u064a\u0632\u0629 \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u0629 \u0644\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u064a\u0648\u0645\u064a \u0645\u0646\u0630 \u0633\u0646\u0648\u0627\u062a \u0637\u0648\u064a\u0644\u0629\u061b \u0625\u0630 \u064a\u062d\u0641\u0651\u0632 \u0627\u0644\u062c\u0633\u0645 \u0639\u0644\u0649 \u0625\u0646\u062a\u0627\u062c \u0645\u0632\u064a\u062f \u0645\u0646 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 \u0627\u0644\u062c\u0646\u064a\u0646\u064a \u0627\u0644\u0630\u064a \u064a\u0642\u0627\u0648\u0645 \u0627\u0644\u062a\u0634\u0643\u0651\u0644 \u0627\u0644\u0645\u0646\u062c\u0644\u064a\u060c \u0648\u064a\u064f\u0642\u0644\u0651\u0644 \u0645\u0646 \u062a\u0643\u0631\u0627\u0631 \u0623\u0632\u0645\u0627\u062a \u0627\u0644\u0623\u0644\u0645 \u0648\u0646\u0648\u0628\u0627\u062a \u0627\u0644\u0635\u062f\u0631 \u0627\u0644\u062d\u0627\u062f\u0629. \u0648\u0645\u0646 \u0627\u0644\u0623\u062f\u0648\u064a\u0629 \u0627\u0644\u0645\u0639\u062a\u0645\u062f\u0629 \u0627\u0644\u0623\u062e\u0631\u0649: \u0625\u0644-\u063a\u0644\u0648\u062a\u0627\u0645\u064a\u0646 (L-glutamine) \u0627\u0644\u0630\u064a \u064a\u064f\u0633\u0627\u0639\u062f \u0639\u0644\u0649 \u062a\u0642\u0644\u064a\u0644 \u0627\u0644\u0623\u0632\u0645\u0627\u062a\u060c \u0648\u0643\u0631\u064a\u0632\u0627\u0646\u0644\u064a\u0632\u0648\u0645\u0627\u0628 (Crizanlizumab) \u0648\u0647\u0648 \u062c\u0633\u0645 \u0645\u0636\u0627\u062f \u064a\u064f\u0639\u0637\u0649 \u0639\u0646 \u0637\u0631\u064a\u0642 \u0627\u0644\u0648\u0631\u064a\u062f \u064a\u0639\u0645\u0644 \u0639\u0644\u0649 \u062a\u062b\u0628\u064a\u0637 \u0628\u0631\u0648\u062a\u064a\u0646 \u064a\u064f\u0639\u0631\u0641 \u0628\u0640 P-selectin \u0644\u0644\u062d\u062f\u0651 \u0645\u0646 \u0627\u0644\u062a\u0635\u0627\u0642 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u062f\u0627\u062e\u0644 \u0627\u0644\u0623\u0648\u0639\u064a\u0629 \u0627\u0644\u062f\u0645\u0648\u064a\u0629. \u0643\u0645\u0627 \u062a\u0634\u0645\u0644 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0627\u0644\u064a\u0648\u0645\u064a\u0629 \u062a\u0646\u0627\u0648\u0644 \u062d\u0645\u0636 \u0627\u0644\u0641\u0648\u0644\u064a\u0643 \u0644\u062f\u0639\u0645 \u0625\u0646\u062a\u0627\u062c \u0643\u0631\u064a\u0627\u062a \u0627\u0644\u062f\u0645 \u0627\u0644\u062d\u0645\u0631\u0627\u0621\u060c \u0648\u062a\u0633\u0643\u064a\u0646 \u0627\u0644\u0623\u0644\u0645 \u0628\u0633\u0631\u0639\u0629 \u062e\u0644\u0627\u0644 \u0627\u0644\u0623\u0632\u0645\u0627\u062a.<\/p>\n

\u062a\u0624\u062f\u064a \u0639\u0645\u0644\u064a\u0627\u062a \u0646\u0642\u0644 \u0627\u0644\u062f\u0645 \u062f\u0648\u0631\u064b\u0627 \u0645\u0647\u0645\u064b\u0627\u060c \u0633\u0648\u0627\u0621 \u0641\u064a \u062d\u0627\u0644\u0627\u062a \u0627\u0644\u0637\u0648\u0627\u0631\u0626 \u0623\u0648 \u0644\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0645\u0636\u0627\u0639\u0641\u0627\u062a \u0643\u0627\u0644\u0633\u0643\u062a\u0629 \u0627\u0644\u062f\u0645\u0627\u063a\u064a\u0629\u060c \u063a\u064a\u0631 \u0623\u0646 \u0639\u0645\u0644\u064a\u0627\u062a \u0627\u0644\u0646\u0642\u0644 \u0627\u0644\u0645\u062a\u0643\u0631\u0631\u0629 \u0642\u062f \u062a\u064f\u0633\u0628\u0651\u0628 \u062a\u0631\u0627\u0643\u0645 \u0627\u0644\u062d\u062f\u064a\u062f \u0641\u064a \u0627\u0644\u062c\u0633\u0645\u060c \u0644\u0630\u0627 \u062a\u0631\u0627\u0642\u0628 \u0641\u0631\u0642 \u0627\u0644\u0631\u0639\u0627\u064a\u0629 \u0645\u0633\u062a\u0648\u0649 \u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0627\u0644\u0630\u064a \u064a\u0639\u0643\u0633 \u0645\u062e\u0632\u0648\u0646 \u0627\u0644\u062d\u062f\u064a\u062f \u0641\u064a \u0627\u0644\u062c\u0633\u0645<\/a> \u0648\u0642\u062f \u062a\u064f\u0636\u0627\u0641 \u0623\u062f\u0648\u064a\u0629 \u0644\u0625\u0632\u0627\u0644\u0629 \u0627\u0644\u062d\u062f\u064a\u062f \u0627\u0644\u0632\u0627\u0626\u062f. \u0648\u0628\u0627\u0644\u0646\u0633\u0628\u0629 \u0644\u0644\u0623\u0637\u0641\u0627\u0644\u060c \u064a\u064f\u0642\u0644\u0651\u0644 \u062a\u0646\u0627\u0648\u0644 \u0627\u0644\u0628\u0646\u0633\u0644\u064a\u0646 \u064a\u0648\u0645\u064a\u064b\u0627 \u0641\u064a \u0627\u0644\u0633\u0646\u0648\u0627\u062a \u0627\u0644\u0623\u0648\u0644\u0649 \u0645\u0646 \u0627\u0644\u0639\u0645\u0631 \u0625\u0644\u0649 \u062c\u0627\u0646\u0628 \u0627\u0644\u0627\u0644\u062a\u0632\u0627\u0645 \u0628\u062c\u062f\u0648\u0644 \u0627\u0644\u062a\u0637\u0639\u064a\u0645\u0627\u062a \u0627\u0644\u0643\u0627\u0645\u0644 \u0645\u0646 \u062e\u0637\u0631 \u0627\u0644\u0625\u0635\u0627\u0628\u0629 \u0628\u0627\u0644\u0639\u062f\u0648\u0649 \u0627\u0644\u0645\u0647\u062f\u062f\u0629 \u0644\u0644\u062d\u064a\u0627\u0629 \u0628\u0634\u0643\u0644 \u0645\u0644\u062d\u0648\u0638.<\/p>\n

\u064a\u064f\u0639\u062f\u0651 \u0648\u0635\u0648\u0644 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u062a\u063a\u064a\u064a\u0631\u064e \u0627\u0644\u0623\u0628\u0639\u062f \u0623\u062b\u0631\u0627\u064b \u0645\u0646\u0630 \u0639\u0642\u0648\u062f. \u0641\u0641\u064a \u062f\u064a\u0633\u0645\u0628\u0631 2023\u060c \u0648\u0627\u0641\u0642\u062a \u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u063a\u0630\u0627\u0621 \u0648\u0627\u0644\u062f\u0648\u0627\u0621 \u0627\u0644\u0623\u0645\u0631\u064a\u0643\u064a\u0629 (FDA) \u0639\u0644\u0649 \u0623\u0648\u0644 \u0639\u0644\u0627\u062c\u064a\u0646 \u062c\u064a\u0646\u064a\u064a\u0646 \u0644\u0645\u0631\u0636 \u0641\u0642\u0631 \u0627\u0644\u062f\u0645 \u0627\u0644\u0645\u0646\u062c\u0644\u064a\u060c \u0648\u0647\u0645\u0627 Casgevy \u0648Lyfgenia\u060c \u0644\u0644\u0623\u0634\u062e\u0627\u0635 \u0627\u0644\u0630\u064a\u0646 \u062a\u0628\u0644\u063a \u0623\u0639\u0645\u0627\u0631\u0647\u0645 12 \u0639\u0627\u0645\u0627\u064b \u0641\u0623\u0643\u062b\u0631 \u0645\u0645\u0646 \u064a\u0639\u0627\u0646\u0648\u0646 \u0645\u0646 \u0646\u0648\u0628\u0627\u062a \u0623\u0644\u0645 \u0645\u062a\u0643\u0631\u0631\u0629. \u0648\u064a\u062a\u0645\u064a\u0632 Casgevy \u0628\u0643\u0648\u0646\u0647 \u0623\u0648\u0644 \u0639\u0644\u0627\u062c \u0645\u0639\u062a\u0645\u062f \u064a\u0639\u062a\u0645\u062f \u0639\u0644\u0649 \u062a\u0642\u0646\u064a\u0629 \u0643\u0631\u064a\u0633\u0628\u0631 (CRISPR) \u0639\u0644\u0649 \u0627\u0644\u0625\u0637\u0644\u0627\u0642\u060c \u0625\u0630 \u064a\u064f\u0639\u062f\u0650\u0651\u0644 \u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u0645\u0631\u064a\u0636 \u0627\u0644\u0645\u0643\u0648\u0650\u0651\u0646\u0629 \u0644\u0644\u062f\u0645 \u0644\u0625\u0639\u0627\u062f\u0629 \u062a\u0641\u0639\u064a\u0644 \u0627\u0644\u0647\u064a\u0645\u0648\u063a\u0644\u0648\u0628\u064a\u0646 \u0627\u0644\u062c\u0646\u064a\u0646\u064a\u060c \u0628\u064a\u0646\u0645\u0627 \u064a\u064f\u0636\u064a\u0641 Lyfgenia \u062c\u064a\u0646\u0627\u064b \u0633\u0644\u064a\u0645\u0627\u064b \u0625\u0644\u0649 \u062a\u0644\u0643 \u0627\u0644\u062e\u0644\u0627\u064a\u0627. \u0648\u0644\u0627 \u064a\u0632\u0627\u0644 \u0632\u0631\u0639 \u0627\u0644\u062e\u0644\u0627\u064a\u0627 \u0627\u0644\u062c\u0630\u0639\u064a\u0629 \u0627\u0644\u062e\u064a\u0641\u064a\u0629\u060c \u0623\u0648 \u0632\u0631\u0639 \u0646\u062e\u0627\u0639 \u0627\u0644\u0639\u0638\u0645 \u0645\u0646 \u0645\u062a\u0628\u0631\u0639 \u0645\u062a\u0648\u0627\u0641\u0642\u060c \u0627\u0644\u0639\u0644\u0627\u062c\u064e \u0627\u0644\u0631\u0627\u0633\u062e \u0627\u0644\u0648\u062d\u064a\u062f \u0627\u0644\u0630\u064a \u064a\u0645\u0643\u0646\u0647 \u0627\u0644\u0634\u0641\u0627\u0621 \u0645\u0646 \u0627\u0644\u0645\u0631\u0636 \u0646\u0647\u0627\u0626\u064a\u0627\u064b. \u0648\u062a\u062c\u062f\u0631 \u0627\u0644\u0625\u0634\u0627\u0631\u0629 \u0625\u0644\u0649 \u0623\u0646 \u062f\u0648\u0627\u0621 \u0641\u0648\u0643\u0633\u064a\u0644\u0648\u062a\u0648\u0631\u060c \u0627\u0644\u0645\u0639\u0631\u0648\u0641 \u062a\u062c\u0627\u0631\u064a\u0627\u064b \u0628\u0627\u0633\u0645 Oxbryta\u060c \u0633\u064f\u062d\u0628 \u0645\u0646 \u0627\u0644\u0623\u0633\u0648\u0627\u0642 \u0627\u0644\u0639\u0627\u0644\u0645\u064a\u0629 \u0641\u064a \u0633\u0628\u062a\u0645\u0628\u0631 2024 \u0645\u0646 \u0642\u0650\u0628\u064e\u0644 \u0627\u0644\u0634\u0631\u0643\u0629 \u0627\u0644\u0645\u0635\u0646\u0650\u0651\u0639\u0629 \u0628\u0633\u0628\u0628 \u0645\u062e\u0627\u0648\u0641 \u062a\u062a\u0639\u0644\u0642 \u0628\u0627\u0644\u0633\u0644\u0627\u0645\u0629\u060c \u0648\u0644\u0645 \u064a\u0639\u062f \u0645\u062a\u0627\u062d\u0627\u064b\u060c \u0648\u0628\u0627\u0644\u062a\u0627\u0644\u064a \u0644\u0645 \u064a\u0639\u062f \u062c\u0632\u0621\u0627\u064b \u0645\u0646 \u062e\u0637\u0637 \u0627\u0644\u0639\u0644\u0627\u062c \u0627\u0644\u062d\u0627\u0644\u064a\u0629.<\/p>\n\n

\u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0627\u0644\u0645\u0636\u0627\u0639\u0641\u0627\u062a \u0648\u0627\u0644\u0625\u062f\u0627\u0631\u0629 \u0627\u0644\u064a\u0648\u0645\u064a\u0629 \u0644\u0644\u0645\u0631\u0636<\/h2>\n

\u0644\u0627 \u064a\u0645\u0643\u0646 \u0627\u0644\u0648\u0642\u0627\u064a\u0629 \u0645\u0646 \u0627\u0644\u062a\u063a\u064a\u064a\u0631 \u0627\u0644\u062c\u064a\u0646\u064a \u0627\u0644\u0623\u0633\u0627\u0633\u064a\u060c \u063a\u064a\u0631 \u0623\u0646 \u0643\u062b\u064a\u0631\u0627\u064b \u0645\u0646 \u0627\u0644\u0646\u0648\u0628\u0627\u062a \u0648\u0627\u0644\u0645\u0636\u0627\u0639\u0641\u0627\u062a \u064a\u0645\u0643\u0646 \u0627\u0644\u062d\u062f\u0651 \u0645\u0646\u0647\u0627 \u0645\u0646 \u062e\u0644\u0627\u0644 \u0631\u0639\u0627\u064a\u0629 \u0645\u0646\u062a\u0638\u0645\u0629 \u0648\u0627\u0633\u062a\u0628\u0627\u0642\u064a\u0629 \u062a\u0631\u0643\u0651\u0632 \u0639\u0644\u0649 \u062a\u062c\u0646\u0651\u0628 \u0627\u0644\u0645\u062d\u0641\u0632\u0627\u062a \u0627\u0644\u0645\u0639\u0631\u0648\u0641\u0629 \u0648\u0627\u0644\u0628\u0642\u0627\u0621 \u0645\u062a\u0642\u062f\u0645\u0627\u064b \u0639\u0644\u0649 \u0627\u0644\u0645\u0634\u0643\u0644\u0627\u062a \u0639\u0628\u0631 \u0632\u064a\u0627\u0631\u0627\u062a \u0637\u0628\u064a\u0629 \u062f\u0648\u0631\u064a\u0629.<\/p>\n